Association Between Severity of Anaphylaxis and Co-occurrence of Respiratory Diseases: A Systematic Review and Meta-analysis of Observational Studies

Background: Asthma is very prevalent in all grades of severity anaphylaxis. and chronic obstructive pulmonary disease (COPD) have been associated with the Objective: We carried out a systematic review meta-analysis to assess influence respiratory diseases on Methods: searched PubMed/MEDLINE, EMBASE, Web Science for observational studies. The target studies were those that compared anaphylaxis between patients who had or did not diseases. Results: A total 13 assessed disease. Respiratory increased (OR, 1.87; 95%CI, 1.30-2.70), as asthma 1.89; 1.26-2.83). For (adjusted nonadjusted), COPD 2.47; 1.46-4.18). In case studies, only 1 study Conclusions: Evidence showing increases low moderate, although do usually importance asthma.